Modal agnosticism is the view that we must be agnostic about whether things could have turned out differently. I argue that claims about unrealised possibilities are not justified by our modal intuitions, nor are they justified by any of the means proposed by philosophers. It follows that we do not have merely metaphysical modal knowledge, and that we must adopt modal agnosticism.

In The Art of Living, Alexander Nehamas argues that Michel de Montaigne, Friedrich Nietzsche, and Michel Foucault undertook a particularist art of living—a unique project of self‐construction. In so doing, argues Nehamas, they based their lives on the life of Socrates, that quintessentially ironic character. To this list of self‐fashioning philosophers, I add Fernando Pessoa, the twentieth‐century Portuguese writer. I argue that Pessoa, via the writings of his heteronyms, also took Socrates as the model for constructing a self. Moreover, Pessoa (...) employed all three kinds of irony that Nehamas argues is present in Plato’s writing, and did so not just to investigate the nature of the self, but to question its very existence. This is Pessoa’s formulation of the problem of the self. But Pessoa also borrowed from Nietzsche’s views on multiplicity, redeploying them in order to fabricate multiple selves. Pessoa’s solution to the problem of the self thus consists in the heteronymic device, which acts as a deus ex machina, unifying the disparate fictional voices and establishing Pessoa as a new, authentic self. Accordingly, Pessoa borrows from both Platonism and anti‐Platonism, distinguishing himself from both, so as to contrive—and simultaneously exemplify—an original art of living. (shrink)

BackgroundObtaining informed consent for intravenous thrombolysis in acute ischemic stroke can be challenging, and little is known about if and how the informed consent procedure is performed by neurologists in clinical practice. This study examines the procedure of informed consent for intravenous thrombolysis in acute ischemic stroke in high-volume stroke centers in the Netherlands.MethodsIn four high volume stroke centers, neurology residents and attending neurologists received an online questionnaire concerning informed consent for thrombolysis with tissue-type plasminogen activator (tPA). The respondents were (...) asked to report their usual informed consent practice for tPA treatment and their considerations on whether informed consent should be obtained.ResultsFrom the 203 invited clinicians, 50% (n = 101) completed the questionnaire. One-third of the neurology residents (n = 21) and 21% of the neurologists (n = 8) reported that they always obtain informed consent for tPA treatment. If a patient is not capable of providing informed consent, 30% of the residents (n = 19) reported that they start tPA treatment without informed consent. In these circumstances, 53% of the neurologists (n = 20) reported that the resident under their supervision would start tPA treatment without informed consent. Most neurologists (n = 21; 55%) and neurology residents (n = 45; 72%) obtained informed consent within one minute. None of the respondents used more than five minutes for informed consent. Important themes regarding obtaining informed consent for treatment were patients’ capacity, and medical, ethical and legal considerations.ConclusionThe current practice of informed consent for thrombolysis in acute ischemic stroke varies among neurologists and neurology residents. If informed consent is obtained, most clinicians stated to obtain informed consent within one minute. In the future, a shortened information provision process may be applied, making a shift from informed consent to informed refusal, while still considering the patient’s capacity, stroke severity, and possible treatment delays. (shrink)

BackgroundIn Pakistan, drug promotion practices, ethical or unethical, have rarely been in the spotlight. We aimed to assess the perception and barriers of medical representatives (MRs) and doctors (MDs) regarding ethical promotion of pharmaceuticals in Pakistan.MethodsA cross sectional survey was conducted in seven major cities of Pakistan for 6-months period. Self-administered questionnaire was used for data collection. Logistic regression and five-point Likert scale scoring was used to estimate the perceptions and barriers.ResultsCompared to national companies (NCs), the medical representatives (MRs) of (...) multinational companies (MNCs) strongly believed that their companies follow World Health Organization (WHO) (OR; 5.31, p = 0.0005), International Federation of Pharmaceutical Manufacturers & Associations (IFPMA) (OR; 6.45, p = 0.0005) and national codes of ethics (OR; 5.84, p = 0.0005). MNCs trained their MRs (OR; 6.68, p = 0.0005), provide accurate and valid scientific data (OR; 4.01, p = 0.007) with adequate system of accountability and controls on product samples (OR; 1.96, p = 0.047), while, NCs sponsor social or entertainment activities, seminars and conferences, and all sort of facilitation in form of gifts of their choice and clinic renovation for medical doctors (MDs). MDs perceptions were similar to MRs mentioned above, yet strongly agreed that companies offer cash payments or equivalents to MDs. The MRs of NCs/mncs and MDs agreed/strongly agreed that no external accountability, profiteering, pressure on sale targets, job insecurity, condoning unethical promotion by high-ups’ and business promotion by junior MDs were the predominant barriers.ConclusionIn conclusion, MRs of MNCs and MDs believed that MNCs follow certain codes of ethics in the promotion of pharmaceuticals, while NCs tend to be more profit oriented and even condone unethical promotion. All stakeholders, MRs, MDs and companies, might pose certain barriers, intentionally or unintentionally, in ethical promotion. (shrink)

The Visser rules form a basis of admissibility for the intuitionistic propositional calculus. We show how one can characterize the existence of covers in certain models by means of formulae. Through this characterization, we provide a new proof of the admissibility of a weak form of the Visser rules. Finally, we use this observation, coupled with a description of a generalization of the disjunction property, to provide a basis of admissibility for the intermediate logics BD2 and GSc.

Product acceptance determination using similarity measure index by neutrosophic statistics / Muhammad Aslam and Rehan Ahmed Khan Sherwani -- New concepts of strongly edge irregular interval-valued neutrosophic graphs / A.A.Talebi, Hossein Rashmanlou and Masoomeh Ghasemi -- The link between neutrosophy and learning : through the related concepts of representation and compression / Philippe Schweizer -- Neutrosophic soft cubic M-subalgebras of B-algebras / Mohsin Khalid, Neha Andaleeb Khalid and Hasan Khalid -- Alpha, beta and gamma product of neutrosophic graphs / (...) Nasir Shah, Said Broumi, Abdul Raheem and Tahir Imran -- Neutrosophic cubic normal ideal and neutrosophic cubic closed normal ideal of PS-algebra / Mohsin Khalid, Hasan khalid and Neha Andaleeb Khalid -- Neutrosophic multisets : an overview / Vakkas Uluçay -- Neutrosophy as a model for knowledge : the influence of representative models on thinking / Philippe Schweizer -- When neutrosophic theory meets three-way decisions / Rui Ren, Chao Zhang and Deyu Li -- Neutrosophic economic order quantity model with more than one price breaks / R. Surya, M. Mullai and G. Madhan Kumar -- General non-square systems of linear equations in single-valued triangular neutrosophic number environment / S.A. Edalatpanah -- Hesitant neutrosophic soft set relations / Abhijit Saha -- Computer application of neutrosophic set operations / S. Saranya, M. Vigneshwaran, Said Broumi -- Triangular bipolar neutrosophic based transportation problem / Avishek Chakraborty -- Studying neutrosophic variables / Rafif Alhabib and Ahmad Salama -- Decision making for logistics center location selection in trapezoidal neutrosophic environment / Kalyan Mondal and Surapati Pramanik -- Weighted similarity measure and decision making model for clinical application of single valued neutrosophic set / R.Binu and P. Isaac -- Rough neutrosophic set : an overview / Surapati Pramanik -- Some new concepts on normalized SVTN-number and multiple criteria decision making / İrfan Deli and Emel Kırmızı Öztürk. (shrink)

Advocates have sought to prove that underdetermination obtains because all theories have empirical equivalents. But algorithms for generating empirical equivalents simply exchange underdetermination for familiar philosophical chestnuts, while the few convincing examples of empirical equivalents will not support the desired sweeping conclusions. Nonetheless, underdetermination does not depend on empirical equivalents: our warrant for current theories is equally undermined by presently unconceived alternatives as well-confirmed merely by the existing evidence, so long as this transient predicament recurs for each theory and body (...) of evidence we consider. The historical record supports the claim that this recurrent, transient underdetermination predicament is our own. (shrink)

The purpose of this study is to examine the relationship between the corporate social performance of an organization and three variables: the size of the organization, the financial performance of the organization, and the environmental performance of the organization. By empirically testing data from 1987 to 1992, the results of the study show that a firm's corporate social performance is indeed impacted by the size of the firm, the level of profitability of the firm, and the amount of pollution emissions (...) released by the firm. (shrink)

It is fortunate for my purposes that English has the two words ‘almighty’ and ‘omnipotent’, and that apart from any stipulation by me the words have rather different associations and suggestions. ‘Almighty’ is the familiar word that comes in the creeds of the Church; ‘omnipotent’ is at home rather in formal theological discussions and controversies, e.g. about miracles and about the problem of evil. ‘Almighty’ derives by way of Latin ‘omnipotens’ from the Greek word ‘pantokratōr’; and both this Greek word, (...) like the more classical ‘pankratēs’, and ‘almighty’ itself suggest God's having power over all things. On the other hand the English word ‘omnipotent’ would ordinarily be taken to imply ability to do everything; the Latin word ‘omnipotens’ also predominantly has this meaning in Scholastic writers, even though in origin it is a Latinization of ‘pantocratōr’. So there already is a tendency to distinguish the two words; and in this paper I shall make the distinction a strict one. I shall use the word ‘almighty’ to express God's power over all things, and I shall take ‘omnipotence’ to mean ability to do everything. (shrink)

By the time of his death in 2006, Sir Peter Strawson was regarded as one of the world's most distinguished philosophers. Unavailable for many years,_ Scepticism and Naturalism_ is a profound reflection on two classic philosophical problems by a philosopher at the pinnacle of his career. Based on his acclaimed Woodbridge lectures delivered at Columbia University in 1983, Strawson begins with a discussion of scepticism, which he defines as questioning the adequacy of our grounds for holding various beliefs. He then (...) draws deftly on Hume and Wittgenstein to argue that we must distinguish between 'hard', scientific naturalism; or 'soft', humanistic naturalism. In the remaining chapters the author takes up several issues in which sceptical doubts play an important role, in particular the nature of transcendental arguments and including the objectivity of moral philosophy, the mental and the physical, and the existence of abstract entities. _Scepticism and Naturalism_ is essential reading for those seeking an introduction to the work of one of the twentieth century’s most important and original philosophers. This reissue includes a substantial new foreword by Quassim Cassam and a fascinating intellectual autobiography by Strawson, which together form an excellent introduction to his life and work. (shrink)

This fourth and final volume of the monumental commentary on Wittgenstein's _Philosophical Investigations_ covers pp 428-693 of the book. Like the previous volumes, it consists of philosophical essays and exegesis.

The current paper highlights a new, interactive Shiny App that can be used to aid in understanding and teaching the important task of conducting a prior sensitivity analysis when implementing Bayesian estimation methods. In this paper, we discuss the importance of examining prior distributions through a sensitivity analysis. We argue that conducting a prior sensitivity analysis is equally important when so-called diffuse priors are implemented as it is with subjective priors. As a proof of concept, we conducted a small simulation (...) study, which illustrates the impact of priors on final model estimates. The findings from the simulation study highlight the importance of conducting a sensitivity analysis of priors. This concept is further extended through an interactive Shiny App that we developed. The Shiny App allows users to explore the impact of various forms of priors using empirical data. We introduce this Shiny App and thoroughly detail an example using a simple multiple regression model that users at all levels can understand. In this paper, we highlight how to determine the different settings for a prior sensitivity analysis, how to visually and statistically compare results obtained in the sensitivity analysis, and how to display findings and write up disparate results obtained across the sensitivity analysis. The goal is that novice users can follow the process outlined here and work within the interactive Shiny App to gain a deeper understanding of the role of prior distributions and the importance of a sensitivity analysis when implementing Bayesian methods. The intended audience is broad and can include those with limited exposure to Bayesian methods or the specific model presented here. (shrink)

We prove that all extensions of Heyting Arithmetic with a logic that has the finite frame property possess the de Jongh property.

First published in 1987. Routledge is an imprint of Taylor & Francis, an informa company.

Knowing Persons is an original study of Plato's account of personhood. For Plato, embodied persons are images of a disembodied ideal. The ideal person is a knower. Hence, the lives of embodied persons need to be understood according to Plato's metaphysics of imagery.For Gerson, Plato's account of embodied personhood is not accurately conflated with Cartesian dualism. Plato's dualism is more appropriately seen in the contrast between the ideal disembodied person and the embodied one than in the contrast between mind or (...) soul and body.This study argues that Plato's analysis of personhood is intended to cohere with his two-world metaphysics as well as a radical separation of knowledge and belief. Gerson demonstrates that Plato's account of persons plays a key role not just in his theory of mind, but in his theory of knowledge, his metaphysics, and his ethics. A proper understanding of Plato's account of persons must therefore place it in the context of his doctrines in these areas. Knowing Persons fills a significant gap by showing the way to such an understanding. (shrink)

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By the time of his death in 2006, Sir Peter Strawson was regarded as one of the world's most distinguished philosophers. Unavailable for many years,_ Scepticism and Naturalism_ is a profound reflection on two classic philosophical problems by a philosopher at the pinnacle of his career. Based on his acclaimed Woodbridge lectures delivered at Columbia University in 1983, Strawson begins with a discussion of scepticism, which he defines as questioning the adequacy of our grounds for holding various beliefs. He then (...) draws deftly on Hume and Wittgenstein to argue that we must distinguish between 'hard', scientific naturalism; or 'soft', humanistic naturalism. In the remaining chapters the author takes up several issues in which sceptical doubts play an important role, in particular the nature of transcendental arguments and including the objectivity of moral philosophy, the mental and the physical, and the existence of abstract entities. _Scepticism and Naturalism_ is essential reading for those seeking an introduction to the work of one of the twentieth century’s most important and original philosophers. This reissue includes a substantial new foreword by Quassim Cassam and a fascinating intellectual autobiography by Strawson, which together form an excellent introduction to his life and work. (shrink)

We investigate the theory IΔ 0 + Ω 1 and strengthen [Bu86. Theorem 8.6] to the following: if NP ≠ co-NP. then Σ-completeness for witness comparison formulas is not provable in bounded arithmetic. i.e. $I\delta_0 + \Omega_1 + \nvdash \forall b \forall c (\exists a(\operatorname{Prf}(a.c) \wedge \forall = \leq a \neg \operatorname{Prf} (z.b))\\ \rightarrow \operatorname{Prov} (\ulcorner \exists a(\operatorname{Prf}(a. \bar{c}) \wedge \forall z \leq a \neg \operatorname{Prf}(z.\bar{b})) \urcorner)).$ Next we study a "small reflection principle" in bounded arithmetic. We prove that for (...) all sentences φ $I\Delta_0 + \Omega_1 \vdash \forall x \operatorname{Prov}(\ulcorner \forall y \leq \bar{x} (\operatorname{Prf} (y. \overline{\ulcorner \varphi \urcorner}) \rightarrow \varphi)\urcorner).$ The proof hinges on the use of definable cuts and partial satisfaction predicates akin to those introduced by Pudlak in [Pu86]. Finally, we give some applications of the small reflection principle, showing that the principle can sometimes be invoked in order to circumvent the use of provable Σ-completeness for witness comparison formulas. (shrink)

Geared toward readers already acquainted with special relativity, this book transcends the view of theory as a working tool to answer natural questions: What is ...

The logic of information flow has applications in both computer science and natural language processing and is a growing area within mathematical and philosophical logic.

We develop and apply a multi-dimensional conception of explanatory depth towards a comparative analysis of inflationary and bouncing paradigms in primordial cosmology. Our analysis builds on earlier work due to Azhar and Loeb (2021) that establishes initial condition fine-tuning as a dimension of explanatory depth relevant to debates in contemporary cosmology. We propose dynamical fine-tuning and autonomy as two further dimensions of depth in the context of problems with instability and trans-Planckian modes that afflict bouncing and inflationary approaches respectively. In (...) the context of the latter issue, we argue that the recently formulated trans-Planckian censorship conjecture leads to a trade-off for inflationary models between dynamical fine-tuning and autonomy. We conclude with the suggestion that explanatory preference with regard to the different dimensions of depth is best understood in terms of differing attitudes towards heuristics for future model building. (shrink)